Weapons manufacturing for different races

<img src="/files/u22/skills2.jpg" alt="Characters" height="196" width="351" /><br />Notice the Vrusk is holding a specifically designed Vrusken laser rifle?<br />If say a Human or Yazirian were to use the same weapon would they have a to-hit penalty?<br /><br />-OR-<br /><br />If they have a skill in that type of weapon it's assumed they know how to use it no matter the race is was manufactured for?